연구개발

글로벌 유전자·세포치료제 개발을 선도하는 바이오 혁신기업

논문

No. Title
12 Bashyal N., Lee YJ  et al., Assessment of Risks and Benefits of Using Antibiotics Resistance Genes in Mesenchymal Stem Cell-Based Ex-vivo Therapy Int. J. Stem Cell.
11 Bashyal N, Kim MG et al., Preclinical Study on Biodistribution of Mesenchymal Stem Cells after Local Transplantation into the Brain. Int J. Stem Cell (In press) 
10 Kim MG, Lee YJ et al., Enhanced antitumor efficacy of mesenchymal stem cells expressing cytosine deaminase and 5-fluorocytosine combined with α-galactosylceramide in a colon
cancer model. Am J Cancer Res. 2023, 13:2439-2451
9 Lee YJ, Kim MG, et al., THOC2 expression and its impact on 5-fluorouracil resistance in glioblastoma multiforme. Am J Cancer Res. 2023 13:2410-2425. 
8 Bashyal N., et al., Improving the safety of mesenchymal stem cell-based ex vivo therapy using Herpes Simplex virus thymidine kinase. Mol. Cells. 2022, 5:479-494. 
7 Choi JM, Acharya R et al., Cell type-specific knockout with Gli1-mediated Cre recombination in the developing cerebellum Exp Neurobiol, 2021 30:203-212.  
6 Lee TY et al., ERK Regulates NeuroD1-mediated Neurite Outgrowth via Proteasomal Degradation. Exp Neurobiol. 2020, 29:189-206. 
5 Han JH et al., CXCR4-STAT3 Axis Plays a Role in Tumor Cell Infiltration in an Orthotopic Mouse Glioblastoma Model. Mol Cells. 2020, 43:539-550 
4 Chang DY et al., Combined effects of mesenchymal stem cells carrying cytosine deaminase gene with 5-fluorocytosine and temozolomide in orthotopic glioma model. Am J Cancer
Res. 2020, 10:1429-1441 
3 Kim GH et al., Neurogenin-1 Overexpression Increases the Therapeutic Effects of Mesenchymal Stem Cells through Enhanced Engraftment in an Ischemic Rat Brain. Int J Stem Cells.
2020, 13:127-141. 
2 Cha HL et al., Deletion of the α subunit of the heterotrimeric Go protein impairs cerebellar cortical development in mice. Mol Brain. 2019 12:57.  
1 Yoon JS et al., Spatiotemporal Protein Atlas of Cell Death-Related Molecules in the Rat MCAO Stroke Model. Exp Neurobiol. 2018, 7:287-298